Telomeres and atherosclerosis : review article
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چکیده
منابع مشابه
Telomeres and atherosclerosis
In humans and other multicellular organisms that have an extended lifespan, the leading causes of death are atherosclerotic cardiovascular disease and cancer. Experimental and clinical evidence indicates that these age-related disorders are linked through dysregulation of telomere homeostasis. Telomeres are DNA protein structures located at the terminal end of chromosomes and shorten with each ...
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Although the level and pace of population aging display high geographical variability, virtually all countries have been experiencing growth in their elderly population, particularly in developed nations. Because aging is a major risk factor for atherosclerosis and associated disease, it is of up most importance to unravel the molecular mechanisms involved in vascular aging. Telomeres are speci...
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Human telomere length, as expressed in leukocytes, is strongly fashioned by heritability. A number of genes that explain some of the inter-individual variation in leukocyte telomere length have already been identified. Leukocyte telomere length is longer in women than in men and in African Americans than in whites of european descent. in addition, offspring of older fathers display a longer leu...
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ژورنال
عنوان ژورنال: Cardiovascular Journal Of Africa
سال: 2012
ISSN: 1995-1892,1680-0745
DOI: 10.5830/cvja-2012-056